Intelligence / Tirzepatide

Tirzepatide

Prescription Only
GLP-1/GIP Agonist
Schedule
S4
Prescription Only
Enforcement
Tightening
Medium Risk
Providers
8
Access: Emerging
Key Facts
Schedule 4 - Prescription Only
Dual GLP-1/GIP receptor agonist
Mounjaro is TGA-approved
Compounding pathway under review
Grey market supply increasing

Overview

Tirzepatide is a dual GLP-1/GIP receptor agonist. The branded product Mounjaro has received TGA approval in Australia. The compounding pathway for tirzepatide is currently under review, and grey market supply has been increasing.

Australian Scheduling

Schedule 4 (Prescription Only). Mounjaro is TGA-approved and ARTG-listed. Compounding pathway is under active regulatory review. The TGA is monitoring the grey market supply closely.

Access Pathway

Available through telehealth providers and compounding pharmacies, though fewer providers offer it compared to semaglutide. The compounding pathway may face restrictions. Grey market availability is increasing but carries significant risk.

Regulatory Notice

For informational purposes only. TGA scheduling may change without notice. All Schedule 4 peptides require a valid prescription from a registered Australian medical practitioner. This site does not sell, supply, or facilitate access to therapeutic goods. Data compiled from TGA SUSMP, public provider directories, and publicly available review platforms.

News & Updates20 items
Accidental intradermal injection of tirzepatide associated with increased adverse events
Postgraduate Medical Journal27 July 2026
Once-weekly tirzepatide in patients with obesity and type 2 diabetes trial posted on ClinicalTrials.gov
ClinicalTrials.gov27 July 2026
Severe hypercalcemia in a patient taking tirzepatide: Potential risk factors
Cureus26 July 2026
Semaglutide and tirzepatide linked to fewer alcohol-related hospital visits
News-Medical24 July 2026
Tirzepatide-Induced Weight Loss and Exacerbation of Bipolar Disorder With Clozapine Treatment: A Case Report
Journal of Clinical Psychopharmacology24 July 2026
Comparative Efficacy and Safety of Tirzepatide in Asian and Non-Asian Adults With Obesity Without Diabetes: A Systematic Review and Meta-Analysis.
Endocrinology, diabetes & metabolism23 July 2026
Multi-target-directed drugs: new additions in 2025 and post-marketing safety surveillance of drugs marketed in 2022-2024.
Pharmacological reports : PR22 July 2026
Cardiovascular Outcomes of GLP-1-Based Medicines Among People With Overweight and Obesity: An Umbrella Review of Meta-Analyses of Randomized Controlled Trials.
Obesity reviews : an official journal of the International Association for the Study of Obesity22 July 2026
Obese and overweight patients with type 2 diabetes mellitus are not treated optimally - is it time to reconsider clinical practice?
Expert review of clinical pharmacology17 July 2026
Evolving utilization of bariatric surgery since the rise of semaglutide and tirzepatide.
Surgical endoscopy17 July 2026
Comparative Cardiovascular Outcomes of Tirzepatide and Glucagon-Like Peptide-1 Receptor Agonists in Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease.
Journal of the American Heart Association17 July 2026
Tirzepatide as a therapeutic tool for kidney impairment in obesity: insights from a real-world study.
Journal of translational medicine16 July 2026
Off-label GLP-1 receptor agonist and tirzepatide use for weight loss: patient safety and regulatory oversight
Annals of medicine and surgery (2012)15 July 2026
Case Report: Dramatic metabolic improvement with tirzepatide in a patient with acquired partial lipodystrophy following hematopoietic stem cell transplantation
Frontiers in endocrinology15 July 2026
Comparative effectiveness of tirzepatide and DPP-4 inhibitors in type 2 diabetes with heart failure
Diabetes & vascular disease research15 July 2026
Resolution of anhedonia-like symptoms in patients treated for obesity with tirzepatide: A three-case series
Obesity pillars14 July 2026
Understanding reasons for initiation and experience with tirzepatide among individuals with obesity or overweight: PERCEPTIONS survey results
Obesity Pillars11 July 2026
Lower fall and femoral fracture risks with semaglutide and tirzepatide compared with DPP-4 inhibitors in older adults with type 2 diabetes
Osteoporosis International11 July 2026
Tirzepatide compared with semaglutide in obesity disease: a subpopulation analysis applying Japan Society for the Study of Obesity criteria in the global SURMOUNT-5 trial
Current Medical Research and Opinion11 July 2026
Influence without medical expertise: a social network analysis of Mounjaro discussions on X
Saudi Pharmaceutical Journal10 July 2026

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